Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dctASodium:dicarboxylate symporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (425 aa)    
Predicted Functional Partners:
Swit_2883
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; Belongs to the GST superfamily.
     
 0.566
Swit_1311
TIGRFAM: Succinate dehydrogenase, hydrophobic membrane anchor; PFAM: succinate dehydrogenase, cytochrome b subunit.
  
  
 0.546
Swit_0771
Molecular chaperone-like protein.
   
 0.481
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.477
Swit_2885
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
       0.444
Swit_2131
PFAM: band 7 protein.
   
 0.429
Swit_2355
Band 7 protein; HflC and HflK could regulate a protease.
   
 0.429
Swit_2356
HflK protein; HflC and HflK could encode or regulate a protease.
   
 0.429
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
  0.428
Swit_0265
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase.
     
 0.421
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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