Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_3030PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase. (1169 aa)    
Predicted Functional Partners:
Swit_3235
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.936
Swit_3236
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.934
Swit_3237
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding.
  
 
 0.931
Swit_1709
Assimilatory nitrate reductase (NADH) alpha subunit apoprotein; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; BFD domain protein [2Fe-2S]-binding domain protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 
 0.715
Swit_1473
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region.
  
 
 0.615
Swit_1174
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.606
Swit_1834
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.606
Swit_2022
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.606
Swit_1475
PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit.
   
 
 0.590
Swit_2986
TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit.
   
 
 0.590
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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