Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_3055PFAM: alpha/beta hydrolase fold. (277 aa)    
Predicted Functional Partners:
Swit_1445
PFAM: alpha/beta hydrolase fold.
  
   
 0.769
Swit_1546
PFAM: alpha/beta hydrolase fold.
  
     0.765
Swit_1572
PFAM: alpha/beta hydrolase fold.
  
   
 0.760
Swit_0886
PFAM: alpha/beta hydrolase fold.
  
     0.749
Swit_0910
PFAM: alpha/beta hydrolase fold.
  
     0.748
Swit_3056
Rieske (2Fe-2S) domain protein; PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
   
 
 0.678
Swit_3057
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
  
  
 0.654
Swit_1653
PFAM: alpha/beta hydrolase fold.
  
     0.640
Swit_1070
TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold; Carboxymuconolactone decarboxylase; Ndr family protein.
 
  
 0.616
Swit_3058
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain.
     
 0.602
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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