Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_3059TIGRFAM: gentisate 1,2-dioxygenase; PFAM: Cupin 2, conserved barrel domain protein. (349 aa)    
Predicted Functional Partners:
Swit_0819
Gentisate 1,2-dioxygenase; PFAM: Cupin 2, conserved barrel domain protein.
  
  
 
0.910
Swit_3057
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
 
   
 0.780
Swit_3060
PFAM: fumarylacetoacetate (FAA) hydrolase.
     
 0.743
Swit_3056
Rieske (2Fe-2S) domain protein; PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
 
   
 0.728
Swit_3058
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain.
 
   
 0.698
maiA
Asp/Glu racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
 
     0.651
Swit_3061
PFAM: monooxygenase, FAD-binding.
 
  
 0.648
Swit_3064
PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.
 
   
 0.565
Swit_4258
Gentisate 1 2-dioxygenase-like protein.
  
     0.565
Swit_2311
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
   
 0.555
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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