Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
Swit_3063PFAM: amidohydrolase 2. (333 aa)    
Predicted Functional Partners:
Swit_3064
PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.
 
  
 0.992
Swit_3066
PFAM: Dimethylmenaquinone methyltransferase.
 
   
 0.863
Swit_3065
Demethylmenaquinone methyltransferase-like protein.
 
   
 0.855
Swit_0386
PFAM: amidohydrolase 2.
  
     0.739
Swit_3062
Phthalate 4,5-dioxygenase; PFAM: Rieske [2Fe-2S] domain protein.
 
     0.735
Swit_1617
PFAM: amidohydrolase 2.
  
     0.717
Swit_3061
PFAM: monooxygenase, FAD-binding.
 
  
 0.696
Swit_4311
PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.
 
   
 0.668
Swit_1684
PFAM: monooxygenase, FAD-binding.
 
  
 0.612
Swit_3417
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase.
 
  
 0.575
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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