Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_3111PFAM: HNH endonuclease; SMART: HNH nuclease. (188 aa)    
Predicted Functional Partners:
Swit_3110
PFAM: glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.728
Swit_3109
Hypothetical protein.
       0.628
Swit_3112
PFAM: type IV pilus assembly PilZ.
  
  
 0.559
Swit_4576
PFAM: DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family.
 
  
 0.527
Swit_4471
PFAM: Protein of unknown function DUF1790.
 
    0.516
Swit_3666
PFAM: peptidase S16, lon domain protein.
  
    0.432
Swit_3108
TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
       0.426
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.402
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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