Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_3189PFAM: TonB-dependent receptor; TonB-dependent receptor, plug. (623 aa)    
Predicted Functional Partners:
Swit_0259
PFAM: periplasmic binding protein.
 
  
 0.729
Swit_0258
PFAM: transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
   
 0.721
Swit_0257
PFAM: ABC transporter related; SMART: AAA ATPase.
 
   
 0.601
Swit_3748
TIGRFAM: TonB family protein.
 
 
 
 0.563
Swit_3419
PFAM: TonB-dependent receptor.
 
   
 0.554
Swit_4738
PFAM: TonB-dependent receptor.
 
   
 0.523
Swit_1868
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
   
 0.466
Swit_4047
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.463
Swit_2441
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.462
Swit_1596
Outer membrane receptor protein mostly Fe transport-like protein.
 
   
 0.444
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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