Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_3238PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family. (281 aa)    
Predicted Functional Partners:
Swit_2975
Citryl-CoA lyase; PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.922
Swit_0956
PFAM: MaoC domain protein dehydratase.
 
  
 0.860
Swit_4287
PFAM: malonate decarboxylase delta subunit.
  
  
 0.809
mdcB
Triphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.
 
  
 0.799
Swit_3236
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
  
 0.686
Swit_1729
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
  
  
 0.616
Swit_3235
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.610
Swit_0947
PFAM: class II aldolase/adducin family protein.
  
  
 0.602
Swit_1648
PFAM: class II aldolase/adducin family protein.
  
  
 0.602
Swit_2702
PFAM: class II aldolase/adducin family protein.
  
  
 0.602
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (8%) [HD]