Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_3248PFAM: histone deacetylase superfamily. (369 aa)    
Predicted Functional Partners:
Swit_0794
PFAM: Tetratricopeptide TPR_4.
   
 0.805
Swit_1494
SMART: nuclear protein SET.
  
 0.805
Swit_4155
PFAM: amine oxidase; FAD dependent oxidoreductase.
   
 0.801
Swit_0196
PFAM: SNF2-related protein; helicase domain protein; type III restriction enzyme, res subunit; SMART: DEAD-like helicases-like.
   
 0.796
Swit_3839
Hypothetical protein.
    
 0.795
Swit_3249
Hypothetical protein.
       0.773
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
 
 
 
 0.727
Swit_0885
Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
    
 
 0.691
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
 0.667
Swit_2821
PFAM: Ankyrin.
   
 0.656
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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