Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_3316PFAM: AMP-dependent synthetase and ligase. (608 aa)    
Predicted Functional Partners:
Swit_3317
PFAM: acyl-CoA dehydrogenase domain protein.
 
  
 0.864
Swit_3321
Acetyl-CoA acetyltransferase-like protein.
 
 
 0.861
Swit_3320
PFAM: MaoC domain protein dehydratase.
 
   
 0.855
Swit_3319
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain.
  
  
 0.841
Swit_3318
PFAM: protein of unknown function DUF35.
 
    0.827
Swit_3315
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type.
     
 0.557
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.519
Swit_0038
PFAM: phosphoesterase, PA-phosphatase related.
    
 0.482
Swit_2405
PFAM: phosphoesterase, PA-phosphatase related.
    
 0.482
Swit_3313
PFAM: short-chain dehydrogenase/reductase SDR; KR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.481
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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