Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_3353PFAM: DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. (314 aa)    
Predicted Functional Partners:
Swit_3352
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain.
       0.778
Swit_1578
PFAM: DNA methylase N-4/N-6 domain protein; SMART: ParB domain protein nuclease; Belongs to the N(4)/N(6)-methyltransferase family.
 
  
 0.650
Swit_3355
PFAM: short-chain dehydrogenase/reductase SDR; KR.
       0.556
Swit_3354
PFAM: luciferase family protein.
       0.543
Swit_2540
PFAM: response regulator receiver.
 
  
 0.527
Swit_2199
PFAM: D12 class N6 adenine-specific DNA methyltransferase.
 
  
 0.521
Swit_3351
Hypothetical protein.
       0.475
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.400
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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