Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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[Homology]
Score
Swit_3440Multi-sensor signal transduction histidine kinase; TIGRFAM: PEP-CTERM system histidine kinase, putative; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein. (708 aa)    
Predicted Functional Partners:
Swit_3441
Two component, sigma54 specific, transcriptional regulator, Fis family; TIGRFAM: PEP-CTERM system response regulator, putative; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase.
 
 
 
 0.960
Swit_3439
PFAM: sugar transferase.
 
   
 0.856
Swit_2540
PFAM: response regulator receiver.
   
 
 0.838
Swit_4028
Hypothetical protein.
 
 
 0.823
Swit_4032
TIGRFAM: PEP-CTERM locus polysaccharide chain length determinant; PFAM: lipopolysaccharide biosynthesis protein.
 
   
 0.791
Swit_4036
TIGRFAM: PEP-CTERM locus, polysaccharide deactylase; PFAM: polysaccharide deacetylase.
 
   
 0.786
Swit_4038
PFAM: glycosyl transferase, group 1.
 
   
 0.780
Swit_4031
PFAM: polysaccharide export protein.
 
   
 0.779
Swit_4037
Hypothetical protein.
 
   
 0.779
Swit_4820
PFAM: O-antigen polymerase.
 
   
 0.775
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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