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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Score
Swit_3442PFAM: protein of unknown function DUF815. (278 aa)    
Predicted Functional Partners:
Swit_3441
Two component, sigma54 specific, transcriptional regulator, Fis family; TIGRFAM: PEP-CTERM system response regulator, putative; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase.
  
    0.748
Swit_3440
Multi-sensor signal transduction histidine kinase; TIGRFAM: PEP-CTERM system histidine kinase, putative; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein.
       0.732
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.596
Swit_3007
PFAM: Prephenate dehydrogenase; NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein.
 
     0.567
Swit_3439
PFAM: sugar transferase.
       0.475
Swit_0610
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein.
 
     0.444
Swit_4078
Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR.
  
     0.410
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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