Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_3465TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein. (400 aa)    
Predicted Functional Partners:
Swit_1519
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein.
 
  
 0.859
Swit_2925
PFAM: EAL domain protein.
   
 0.793
Swit_1126
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein.
 
   
 0.790
Swit_2513
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein.
 
   
 0.790
Swit_1316
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Two component regulator propeller; Two component regulator three Y domain protein.
 
 
 0.771
Swit_1477
Putative adenylate/guanylate cyclase; TIGRFAM: PAS sensor protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein.
 
 
 0.557
Swit_0108
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein.
 
 
0.533
Swit_2927
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein.
 
 
0.533
Swit_3968
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; type IV pilus assembly PilZ.
 
 
0.526
Swit_1496
Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; CHASE4 domain protein.
 
 
0.522
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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