Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nbaC3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (183 aa)    
Predicted Functional Partners:
Swit_3524
Aminocarboxymuconate-semialdehyde decarboxylase; PFAM: amidohydrolase 2.
 
  
  0.995
Swit_1683
PFAM: amidohydrolase 2.
 
  
  0.974
Swit_2308
PFAM: amidohydrolase 2.
 
  
  0.974
Swit_1753
PFAM: amidohydrolase 2.
 
  
  0.973
Swit_2313
PFAM: amidohydrolase 2.
 
  
  0.972
Swit_3522
PFAM: Endoribonuclease L-PSP.
 
    0.939
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
  
  0.927
Swit_0269
PFAM: Catalase domain protein.
    
  0.902
Swit_3730
PFAM: Catalase domain protein; Belongs to the catalase family.
    
  0.902
Swit_3519
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
   
 0.875
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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