Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Swit_35384Fe-4S ferredoxin, iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (112 aa)    
Predicted Functional Partners:
Swit_3236
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.970
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.904
Swit_3237
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding.
  
 
 0.833
Swit_3540
PFAM: helicase domain protein.
       0.737
Swit_3235
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.708
Swit_3537
Transcriptional regulator, CarD family; PFAM: transcription factor CarD.
     
 0.687
cysC
Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
     
 0.676
Swit_4672
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.676
Swit_3539
PFAM: RNA-binding S4 domain protein.
       0.650
Swit_3541
PFAM: peptidase M23B.
       0.639
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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