Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_3574Hypothetical protein. (148 aa)    
Predicted Functional Partners:
Swit_3572
Hpr(Ser) kinase/phosphatase.
       0.836
Swit_3573
Hypothetical protein.
       0.836
Swit_3571
Hypothetical protein.
       0.830
Swit_3575
Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein.
       0.745
Swit_3570
Aminodeoxychorismate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein.
       0.709
Swit_3576
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
       0.676
Swit_3577
Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein.
       0.676
Swit_3569
Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR.
       0.558
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
       0.475
Swit_1102
TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component.
       0.475
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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