Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Swit_3595PFAM: major facilitator superfamily MFS_1. (438 aa)    
Predicted Functional Partners:
Swit_2492
PFAM: AMP-dependent synthetase and ligase.
    
 0.869
Swit_4372
PFAM: AMP-dependent synthetase and ligase.
    
 0.799
Swit_1530
PFAM: AMP-dependent synthetase and ligase.
    
 0.773
Swit_3594
TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.626
Swit_1448
PFAM: AMP-dependent synthetase and ligase.
    
 0.612
Swit_3306
PFAM: AMP-dependent synthetase and ligase.
    
 0.585
Swit_3592
PFAM: molybdopterin biosynthesis MoaE protein.
       0.520
Swit_3593
TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein.
       0.520
Swit_3591
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.505
Swit_1016
PFAM: AMP-dependent synthetase and ligase.
    
 0.478
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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