Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_3770PFAM: AMP-dependent synthetase and ligase. (505 aa)    
Predicted Functional Partners:
Swit_3769
PFAM: NAD-dependent epimerase/dehydratase.
  
 
 0.754
Swit_3768
Hypothetical protein.
  
    0.671
Swit_3772
PFAM: 2OG-Fe(II) oxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family.
     
 0.529
ribB-3
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
       0.522
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.519
Swit_0038
PFAM: phosphoesterase, PA-phosphatase related.
    
 0.482
Swit_2405
PFAM: phosphoesterase, PA-phosphatase related.
    
 0.482
Swit_3096
PFAM: ferredoxin; cytochrome P450; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein.
  
 0.470
Swit_3393
PFAM: ferredoxin; cytochrome P450; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein.
  
 0.470
Swit_0829
TIGRFAM: benzoate-CoA ligase family; PFAM: AMP-dependent synthetase and ligase.
 
0.462
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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