Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_3772PFAM: 2OG-Fe(II) oxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family. (348 aa)    
Predicted Functional Partners:
ribB-3
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
  
 0.773
Swit_3769
PFAM: NAD-dependent epimerase/dehydratase.
  
 
 0.551
Swit_3773
PFAM: peptidase S10, serine carboxypeptidase.
  
  
 0.550
Swit_3770
PFAM: AMP-dependent synthetase and ligase.
     
 0.529
Swit_3898
Hypothetical protein.
 
     0.519
Swit_2336
Hypothetical protein.
 
     0.509
Swit_4731
PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding.
     
 0.489
Swit_4830
TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1.
       0.465
Swit_3768
Hypothetical protein.
       0.450
Swit_2749
Hypothetical protein.
 
     0.417
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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