Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_3792PFAM: AMP-dependent synthetase and ligase. (571 aa)    
Predicted Functional Partners:
Swit_3793
PFAM: membrane protein involved in aromatic hydrocarbon degradation.
 
  
 0.803
Swit_3791
Putative transcriptional regulator, MerR family; PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding.
  
  
 0.802
Swit_3796
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
 
 
 0.775
Swit_2949
PFAM: AMP-dependent synthetase and ligase.
 
 
0.751
Swit_2070
PFAM: AMP-dependent synthetase and ligase.
  
  
 
0.711
Swit_0282
PFAM: AMP-dependent synthetase and ligase.
  
  
 
0.708
Swit_3794
Uncharacterized protein.
 
     0.701
Swit_1530
PFAM: AMP-dependent synthetase and ligase.
  
  
 
0.688
Swit_3795
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 
 0.580
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.519
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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