Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_3818PFAM: 4-oxalocrotonate tautomerase. (76 aa)    
Predicted Functional Partners:
Swit_0912
PFAM: Hydratase/decarboxylase.
    
 0.909
Swit_3521
PFAM: Hydratase/decarboxylase.
    
 0.909
Swit_1538
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
    
 0.908
Swit_3519
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.908
Swit_3817
PFAM: protein of unknown function DUF448.
       0.870
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
       0.870
rimP
Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.870
infB
Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
       0.838
Swit_1811
PFAM: polysaccharide deacetylase.
  
     0.724
Swit_2752
Hypothetical protein.
  
     0.695
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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