Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
vapC-3PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (142 aa)    
Predicted Functional Partners:
Swit_3888
Hypothetical protein.
 
 
 
 0.989
Swit_2660
Hypothetical protein.
  
 
 0.868
Swit_1318
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
 
 
 0.617
Swit_3887
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation.
     
 0.603
Swit_3690
Hypothetical protein.
   
   0.596
vapC-2
PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
     0.534
Swit_2425
Plasmid maintenance system antidote protein, XRE family; TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein.
 
   
 0.464
Swit_4882
TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein.
 
   
 0.447
Swit_3890
TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region.
       0.429
Swit_2184
Putative plasmid maintenance system antidote protein, XRE family; TIGRFAM: addiction module antidote protein, HigA family.
 
   
 0.426
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.