STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_3974PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SMART: Prolyl 4-hydroxylase, alpha subunit. (363 aa)    
Predicted Functional Partners:
Swit_3972
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.768
Swit_3973
Putative transmembrane anti-sigma factor.
 
   
 0.766
Swit_3971
Hypothetical protein.
       0.639
purL
Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
       0.479
Swit_3969
PFAM: protein of unknown function DUF559.
       0.414
Swit_1066
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
  
 0.407
Swit_2033
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
  
 0.407
Swit_3225
TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
  
 0.407
Swit_3263
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
  
 0.407
Swit_3561
TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
  
 0.407
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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