Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_3978Exonuclease of the beta-lactamase fold involved in RNA processing-like protein. (371 aa)    
Predicted Functional Partners:
Swit_3979
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase.
 0.989
Swit_0794
PFAM: Tetratricopeptide TPR_4.
    
 0.937
Swit_2792
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like.
 
    0.824
Swit_1186
PFAM: chalcone and stilbene synthase domain protein.
  
 0.808
Swit_3548
ICC-like protein phosphoesterase-like protein.
 
     0.808
Swit_3982
TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain; DNA polymerase LigD, polymerase domain; DNA polymerase LigD, ligase region; PFAM: DNA primase, small subunit; ATP dependent DNA ligase domain protein; ATP dependent DNA ligase.
 
 0.735
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.734
Swit_0140
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; Belongs to the DEAD box helicase family.
  
 0.618
Swit_3798
PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; Belongs to the DEAD box helicase family.
  
 0.618
Swit_4724
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like.
  
 0.618
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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