Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_4047TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (245 aa)    
Predicted Functional Partners:
Swit_0118
PFAM: MotA/TolQ/ExbB proton channel.
 
 
 0.878
Swit_0120
PFAM: Biopolymer transport protein ExbD/TolR.
 
 
 0.872
Swit_4046
PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit.
 
  
 0.846
Swit_0119
Biopolymer transport-like protein.
 
 
 0.789
Swit_1191
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
 
 0.722
Swit_2135
TIGRFAM: Biopolymer transport, TolR; PFAM: Biopolymer transport protein ExbD/TolR.
 
 
 0.652
Swit_2136
TIGRFAM: Tol-Pal system, TolQ; PFAM: MotA/TolQ/ExbB proton channel.
 
 
 0.649
Swit_3766
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
 
 0.619
Swit_2291
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
 
 
 0.608
Swit_1868
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
 
 0.595
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.