Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_4067PFAM: helix-turn-helix domain protein. (125 aa)    
Predicted Functional Partners:
Swit_4066
PFAM: protein of unknown function DUF955.
  
  
 0.811
Swit_4065
PFAM: peptidase C1A, papain.
     
 0.787
Swit_4064
Hypothetical protein.
       0.783
Swit_4068
Hypothetical protein.
       0.773
Swit_4069
Hypothetical protein.
       0.476
Swit_4070
PFAM: Hemolysin-type calcium-binding region.
 
  
 0.439
Swit_1159
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2.
 
 
 0.431
Swit_0804
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver.
 
 
 0.427
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
     
 0.425
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.415
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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