Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_4166Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family. (318 aa)    
Predicted Functional Partners:
Swit_4167
TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
   
 0.727
Swit_1180
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.636
Swit_0254
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.618
Swit_1068
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.615
Swit_2512
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.471
Swit_4168
Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR.
   
 
 0.444
Swit_3308
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding.
  
     0.441
Swit_0653
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; Belongs to the LysR transcriptional regulatory family.
  
     0.421
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
 
 
 0.410
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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