Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
Swit_4182PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (323 aa)    
Predicted Functional Partners:
Swit_4183
PFAM: alpha/beta hydrolase fold.
 
  
 0.867
Swit_4181
PFAM: AMP-dependent synthetase and ligase.
       0.773
Swit_1828
PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain.
  
    0.742
Swit_3337
PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain.
  
    0.741
Swit_3335
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase.
  
     0.709
Swit_1860
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase.
  
     0.703
Swit_3293
Hypothetical protein.
 
     0.703
Swit_1005
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase.
  
     0.696
Swit_0372
Hypothetical protein.
 
  
 0.695
Swit_3090
PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain.
  
    0.695
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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