STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_42275-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase. (276 aa)    
Predicted Functional Partners:
Swit_4228
PFAM: short-chain dehydrogenase/reductase SDR.
  
 
 0.793
Swit_4226
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein.
  
  
 0.791
Swit_4225
5-oxoprolinase (ATP-hydrolyzing); PFAM: Hydantoinase B/oxoprolinase.
       0.754
Swit_4223
PFAM: Carboxylesterase, type B; Belongs to the type-B carboxylesterase/lipase family.
   
 
 0.564
Swit_4229
PFAM: alpha/beta hydrolase fold.
  
  
 0.546
Swit_4224
Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE domain protein.
  
    0.507
Swit_4230
L-lactate dehydrogenase (cytochrome); PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase.
  
  
 0.472
Swit_4222
Hypothetical protein.
   
   0.411
Swit_1557
PFAM: homogentisate 1,2-dioxygenase.
  
  
 0.407
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.407
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: medium (64%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.