Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_4282PFAM: TonB-dependent receptor; TonB-dependent receptor, plug. (739 aa)    
Predicted Functional Partners:
Swit_4318
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
  
 0.703
Swit_1868
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
  
 0.700
Swit_3766
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
  
 0.699
Swit_0540
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
   
 0.638
Swit_4280
Rieske (2Fe-2S) domain protein; PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
       0.636
Swit_4281
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
       0.636
Swit_2291
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
   
 0.630
Swit_4279
2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding.
       0.608
Swit_3144
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
  
 0.577
Swit_3580
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
  
 0.545
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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