Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_4286Hypothetical protein. (536 aa)    
Predicted Functional Partners:
Swit_4288
Acetyl-CoA carboxylase beta subunit-like protein.
 
 
 0.990
Swit_4287
PFAM: malonate decarboxylase delta subunit.
 
  
 0.979
mdcB
Triphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.
 
  
 0.972
Swit_4289
PFAM: malonate decarboxylase gamma subunit.
 
     0.953
Swit_4290
Hypothetical protein.
 
     0.953
Swit_4292
(acyl-carrier-protein) S-malonyltransferase-like protein.
 
  
 0.938
Swit_4285
PFAM: malonate transporter MadL subunit.
 
  
 0.903
Swit_4284
PFAM: malonate/sodium symporter MadM subunit.
 
     0.880
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.808
Swit_4283
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein.
 
     0.617
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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