Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_4301PFAM: major facilitator superfamily MFS_1. (461 aa)    
Predicted Functional Partners:
Swit_4300
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; Belongs to the TPP enzyme family.
     
 0.732
Swit_4298
PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.731
hisC-3
Aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
    0.729
Swit_4297
Phthalate 4,5-dioxygenase; PFAM: Rieske [2Fe-2S] domain protein.
       0.727
Swit_4296
Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR.
     
 0.494
Swit_2287
PFAM: General substrate transporter; major facilitator superfamily MFS_1.
 
   
 0.462
Swit_4302
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
       0.437
Swit_4243
PFAM: General substrate transporter; major facilitator superfamily MFS_1.
  
     0.418
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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