Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_4311PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B. (272 aa)    
Predicted Functional Partners:
Swit_4312
PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase.
 
  
 0.867
Swit_4314
PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
  
  
 0.859
Swit_4313
TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase.
  
  
 0.852
Swit_4308
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase.
  
  
 0.807
Swit_4309
TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase.
  
  
 0.807
Swit_4310
Hypothetical protein.
       0.781
Swit_3064
PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.
 
     0.768
Swit_3063
PFAM: amidohydrolase 2.
 
   
 0.668
Swit_4307
Transcriptional regulator, MarR family; TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR; PFAM: regulatory protein, MarR.
     
 0.581
Swit_4315
Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR.
 
   
 0.535
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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