Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_4316Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR. (152 aa)    
Predicted Functional Partners:
Swit_4312
PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase.
 
   
 0.832
Swit_4315
Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR.
 
     0.769
Swit_4313
TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase.
 
     0.722
Swit_3088
TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase.
  
     0.590
Swit_4271
TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase.
  
     0.560
Swit_4317
TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein.
  
    0.535
Swit_4311
PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.
 
   
 0.492
Swit_4314
PFAM: HpcH/HpaI aldolase; Belongs to the HpcH/HpaI aldolase family.
 
   
 0.474
Swit_3526
PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase.
 
  
 0.436
Swit_0786
PFAM: binding-protein-dependent transport systems inner membrane component; Substrate-binding region of ABC-type glycine betaine transport system.
  
  
 0.428
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (18%) [HD]