STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_4329PFAM: major facilitator superfamily MFS_1. (457 aa)    
Predicted Functional Partners:
Swit_4328
PFAM: short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.786
Swit_3033
PFAM: major facilitator superfamily MFS_1.
 
  
 0.766
Swit_4330
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
       0.683
Swit_4327
3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain protein.
  
  
 0.670
leuD-2
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
     
 0.668
Swit_4323
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
       0.663
Swit_4324
PFAM: short-chain dehydrogenase/reductase SDR; KR.
       0.659
Swit_4325
2,3-dimethylmalate lyase.
       0.658
Swit_4331
Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR.
     
 0.458
Swit_4322
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein.
     
 0.454
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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