Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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[Homology]
Score
Swit_4382PFAM: aldo/keto reductase. (340 aa)    
Predicted Functional Partners:
Swit_4381
PFAM: Endoribonuclease L-PSP.
  
  
 0.636
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
       0.615
Swit_4383
Hypothetical protein.
       0.468
Swit_4379
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein.
       0.450
Swit_0794
PFAM: Tetratricopeptide TPR_4.
   
 0.446
Swit_3248
PFAM: histone deacetylase superfamily.
   
  0.446
Swit_3915
PFAM: histone deacetylase superfamily.
   
  0.446
Swit_4349
PFAM: histone deacetylase superfamily.
   
  0.446
Swit_0771
Molecular chaperone-like protein.
   
 0.445
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.445
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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