Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_4409Peptidase M24; PFAM: creatinase; peptidase M24. (419 aa)    
Predicted Functional Partners:
Swit_4411
PFAM: amino acid permease-associated region.
    
 0.709
Swit_4410
TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; Belongs to the peptidase S33 family.
   
 
 0.627
Swit_4408
PFAM: CHAD domain containing protein; adenylate cyclase.
       0.594
Swit_4407
Hypothetical protein.
       0.577
dadA
D-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family.
  
  
 0.508
Swit_1206
PFAM: sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
     
 0.485
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
 
 
 0.476
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 
 0.467
aroQ
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
  
 0.456
Swit_3142
PFAM: Tetratricopeptide TPR_2 repeat protein.
 
     0.455
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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