Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_4433PFAM: Haloacid dehalogenase domain protein hydrolase. (791 aa)    
Predicted Functional Partners:
Swit_4009
PFAM: glycosyl transferase, group 1; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein.
  
  
 0.632
Swit_3176
Hypothetical protein.
  
     0.584
Swit_4015
PFAM: ABC-2 type transporter.
  
    0.518
Swit_1066
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
     0.515
Swit_4432
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
       0.503
Swit_2033
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
     0.490
Swit_0194
Hypothetical protein.
  
     0.468
Swit_3192
PFAM: Tetratricopeptide TPR_2 repeat protein.
  
     0.456
Swit_2880
UDP-galactopyranose mutase; PFAM: amine oxidase.
 
     0.414
Swit_2398
Hypothetical protein.
 
     0.408
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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