Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Swit_4492PFAM: polysaccharide deacetylase. (321 aa)    
Predicted Functional Partners:
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.870
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
    0.786
Swit_4821
PFAM: glycosyl transferase, group 1.
 
  
 0.668
Swit_4028
Hypothetical protein.
 
   
 0.644
Swit_3710
PFAM: outer membrane efflux protein.
 
     0.597
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
       0.596
Swit_4820
PFAM: O-antigen polymerase.
 
   
 0.596
Swit_4490
Hypothetical protein.
       0.593
Swit_4037
Hypothetical protein.
 
   
 0.573
Swit_0175
Transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; Autoinducer-binding domain protein.
  
  
 0.534
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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