Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Swit_4570PFAM: Pirin domain protein domain protein; Pirin domain protein; Belongs to the pirin family. (296 aa)    
Predicted Functional Partners:
Swit_4569
PFAM: NADPH-dependent FMN reductase.
  
  
 0.810
Swit_4572
PFAM: isochorismatase hydrolase.
  
  
 0.776
Swit_4571
Acetyltransferase-like protein.
  
    0.724
Swit_2867
PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.
 
  
 0.680
Swit_4229
PFAM: alpha/beta hydrolase fold.
  
  
 0.498
Swit_2332
PFAM: heat shock protein DnaJ domain protein.
  
    0.481
Swit_2333
Transcriptional regulator BolA; PFAM: BolA family protein; Belongs to the BolA/IbaG family.
       0.475
Swit_1002
PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein.
 
  
 0.450
Swit_4252
PFAM: 2OG-Fe(II) oxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family.
  
     0.429
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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