Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_4579Hypothetical protein. (101 aa)    
Predicted Functional Partners:
Swit_4580
PFAM: GcrA cell cycle regulator.
       0.675
Swit_0955
Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp.
  
     0.562
parE
DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.556
Swit_0953
Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp.
  
     0.508
Swit_4581
PFAM: ABC-2 type transporter.
       0.504
rnd
Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.
       0.475
Swit_0871
PFAM: Extensin family protein.
  
     0.421
Swit_0870
PFAM: Domain of unknown function DUF1801.
  
     0.413
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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