Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_4585PFAM: GCN5-related N-acetyltransferase. (178 aa)    
Predicted Functional Partners:
Swit_4584
PFAM: protein of unknown function DUF1058.
       0.781
Swit_4583
Glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
       0.551
Swit_3215
PFAM: GCN5-related N-acetyltransferase.
 
     0.519
Swit_4586
PFAM: 3-demethylubiquinone-9 3-methyltransferase.
       0.508
Swit_4587
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
       0.487
Swit_3893
PFAM: GCN5-related N-acetyltransferase.
 
     0.464
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.452
Swit_1088
PFAM: GCN5-related N-acetyltransferase.
 
    
0.413
Swit_2572
Transcriptional regulator, HxlR family; PFAM: helix-turn-helix, HxlR type.
 
     0.401
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (16%) [HD]