Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_4603PFAM: oxidoreductase FAD/NAD(P)-binding domain protein. (323 aa)    
Predicted Functional Partners:
Swit_4058
PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region.
  
 0.998
Swit_4056
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite.
  
 
 0.993
cysC
Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.991
Swit_1210
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.951
Swit_3958
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.951
cysD
TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase.
  
  
 0.939
Swit_3775
PFAM: Rhodanese domain protein.
    
 0.920
metZ
Cystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 
 0.916
Swit_3154
Cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.
  
 
 0.916
Swit_3722
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
 0.904
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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