Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_4609PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein. (331 aa)    
Predicted Functional Partners:
Swit_1819
PFAM: protein of unknown function DUF1611.
 
  
  0.975
Swit_0643
PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
  
  
 
0.912
Swit_1823
PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
  
  
 
0.905
Swit_4610
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein.
 
     0.594
Swit_4612
PFAM: beta-lactamase.
 
  
 0.584
Swit_0976
PFAM: Muconolactone delta-isomerase.
  
  
 0.555
Swit_4607
Acetyl-CoA acetyltransferase-like protein.
  
  
 0.484
Swit_4608
PFAM: AMP-dependent synthetase and ligase.
  
  
 0.472
Swit_0977
TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein.
  
  
 0.457
Swit_1782
PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein.
  
  
 0.457
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (18%) [HD]