Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_4610Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein. (252 aa)    
Predicted Functional Partners:
Swit_1721
Transcriptional regulator, XRE family with cupin sensor; PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein.
 
   
 0.775
Swit_4612
PFAM: beta-lactamase.
 
     0.637
Swit_4611
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
     0.613
Swit_4609
PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein.
 
     0.594
Swit_4613
TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1.
       0.543
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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