Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
Swit_4627PFAM: response regulator receiver. (128 aa)    
Predicted Functional Partners:
Swit_3926
PFAM: histidine kinase, HAMP region domain protein; histidine kinase, dimerisation/phosphoacceptor.
 
   
 0.781
Swit_0073
Response regulator receiver protein.
 
   
 0.753
Swit_1099
Signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation/phosphoacceptor.
 
   
 0.740
Swit_3812
Signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation/phosphoacceptor.
 
   
 0.738
Swit_3435
PFAM: response regulator receiver.
 
   
 0.728
Swit_3924
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.703
Swit_4432
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
  
 0.553
Swit_2540
PFAM: response regulator receiver.
  
  
 0.500
Swit_4628
PFAM: chemotaxis sensory transducer.
     
 0.471
Swit_4530
PFAM: O-antigen polymerase.
 
     0.444
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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