STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutHTIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase. (509 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.987
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.940
Swit_4635
Transcriptional regulator, GntR family; TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein.
 
  
 0.939
Swit_4634
TIGRFAM: formiminoglutamate deiminase; PFAM: amidohydrolase.
 
  
 0.937
Swit_4631
PFAM: N-formylglutamate amidohydrolase.
 
  
 0.908
Swit_1051
Arginase; TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family.
  
  
 0.787
Swit_4629
PFAM: protein of unknown function DUF886.
 
  
 0.736
Swit_1774
Amidohydrolase; PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller.
  
  
 0.519
Swit_1775
Amidohydrolase; PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller; Amidohydrolase 3.
  
  
 0.519
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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