Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_4692Protein-disulfide isomerase-like protein. (241 aa)    
Predicted Functional Partners:
Swit_4691
PFAM: protein of unknown function DUF1159.
 
     0.954
Swit_2548
Disulfide bond formation protein DsbB-like protein.
 
 
 0.819
Swit_4690
A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.
     
 0.780
Swit_4693
Protein-disulfide isomerase-like protein.
 
    
0.777
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
  
 0.764
Swit_4689
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like-like; Zinc ribbon, NADH pyrophosphatase.
       0.760
Swit_0036
ATPase involved in DNA replication initiation; Belongs to the DnaA family.
 
     0.739
Swit_2681
TIGRFAM: Double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
 
     0.716
Swit_2541
Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
   
 0.710
lptD
Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.
 
  
 0.707
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (12%) [HD]