Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Swit_4705PFAM: acid phosphatase (Class B). (294 aa)    
Predicted Functional Partners:
Swit_2353
Hypothetical protein.
 
     0.622
Swit_2433
PFAM: AsmA family protein.
 
     0.579
Swit_0059
Hypothetical protein.
  
     0.539
Swit_0880
Uncharacterized protein.
  
     0.525
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.505
Swit_4689
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like-like; Zinc ribbon, NADH pyrophosphatase.
     
  0.500
Swit_0958
TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase.
       0.475
Swit_0959
TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase.
       0.475
Swit_4704
PFAM: Antibiotic biosynthesis monooxygenase.
       0.473
Swit_4706
PFAM: beta-lactamase.
       0.472
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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